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Mohawk impedes angiofibrosis by preventing the differentiation of tendon stem/progenitor cells into myofibroblasts

Adult tendons heal via fibrovascular scarring with inferior biomechanical properties. Mohawk (Mkx) emerged as a pivotal actor in tenolineage commitment. However, its precise function in tendinopathy remains poorly understood. This study investigates the cellular and molecular mechanisms underlying M...

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Detalles Bibliográficos
Autores principales: Mechakra, Asma, Lin, Junxin, Yang, Yuwei, Du, Xiaotian, Zhang, Jingwei, Ewetse, Paul Maswikitu, Zhou, Feifei, Alakpa, Enateri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678895/
https://www.ncbi.nlm.nih.gov/pubmed/36411329
http://dx.doi.org/10.1038/s41598-022-24195-5