Single-cell RNA sequencing reveals a novel inhibitory effect of ApoA4 on NAFL mediated by liver-specific subsets of myeloid cells

The liver immune microenvironment is a key element in the development of hepatic inflammation in NAFLD. ApoA4 deficiency increases the hepatic lipid burden, insulin resistance, and metabolic inflammation. However, the effect of ApoA4 on liver immune cells and the precise immune cell subsets that exa...

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Detalles Bibliográficos
Autores principales: Liu, Xiao-Huan, Zhou, Jin-Ting, Yan, Chun-xia, Cheng, Cheng, Fan, Jing-Na, Xu, Jing, Zheng, Qiangsun, Bai, Qiang, Li, Zongfang, Li, Shengbin, Li, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678944/
https://www.ncbi.nlm.nih.gov/pubmed/36426356
http://dx.doi.org/10.3389/fimmu.2022.1038401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678944/
https://www.ncbi.nlm.nih.gov/pubmed/36426356
http://dx.doi.org/10.3389/fimmu.2022.1038401

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