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Single-cell RNA sequencing reveals a novel inhibitory effect of ApoA4 on NAFL mediated by liver-specific subsets of myeloid cells
The liver immune microenvironment is a key element in the development of hepatic inflammation in NAFLD. ApoA4 deficiency increases the hepatic lipid burden, insulin resistance, and metabolic inflammation. However, the effect of ApoA4 on liver immune cells and the precise immune cell subsets that exa...
Autores principales: | Liu, Xiao-Huan, Zhou, Jin-Ting, Yan, Chun-xia, Cheng, Cheng, Fan, Jing-Na, Xu, Jing, Zheng, Qiangsun, Bai, Qiang, Li, Zongfang, Li, Shengbin, Li, Xiaoming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678944/ https://www.ncbi.nlm.nih.gov/pubmed/36426356 http://dx.doi.org/10.3389/fimmu.2022.1038401 |
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