Identification and characterization of RBM12 as a novel regulator of fetal hemoglobin expression

The fetal-to-adult hemoglobin transition is clinically relevant because reactivation of fetal hemoglobin (HbF) significantly reduces morbidity and mortality associated with sickle cell disease (SCD) and β-thalassemia. Most studies on the developmental regulation of the globin genes, including genome...

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Detalles Bibliográficos
Autores principales: Wakabayashi, Aoi, Kihiu, Maryanne, Sharma, Malini, Thrasher, A. Josephine, Saari, Megan S., Quesnel-Vallières, Mathieu, Abdulmalik, Osheiza, Peslak, Scott A., Khandros, Eugene, Keller, Cheryl A., Giardine, Belinda M., Barash, Yoseph, Hardison, Ross C., Shi, Junwei, Blobel, Gerd A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678958/
https://www.ncbi.nlm.nih.gov/pubmed/35622975
http://dx.doi.org/10.1182/bloodadvances.2022007904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678958/
https://www.ncbi.nlm.nih.gov/pubmed/35622975
http://dx.doi.org/10.1182/bloodadvances.2022007904

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