Ca(2+) binding to synapsin I regulates resting Ca(2+) and recovery from synaptic depression in nerve terminals

Synapsin I (SynI) is a synaptic vesicle (SV)-associated phosphoprotein that modulates neurotransmission by controlling SV trafficking. The SynI C-domain contains a highly conserved ATP binding site mediating SynI oligomerization and SV clustering and an adjacent main Ca(2+) binding site, whose physi...

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Detalles Bibliográficos
Autores principales: Moschetta, Matteo, Ravasenga, Tiziana, De Fusco, Antonio, Maragliano, Luca, Aprile, Davide, Orlando, Marta, Sacchetti, Silvio, Casagrande, Silvia, Lignani, Gabriele, Fassio, Anna, Baldelli, Pietro, Benfenati, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678998/
https://www.ncbi.nlm.nih.gov/pubmed/36409372
http://dx.doi.org/10.1007/s00018-022-04631-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678998/
https://www.ncbi.nlm.nih.gov/pubmed/36409372
http://dx.doi.org/10.1007/s00018-022-04631-5

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