Cargando…

Hemoglobin is an oxygen-dependent glutathione buffer adapting the intracellular reduced glutathione levels to oxygen availability

Fast changes in environmental oxygen availability translate into shifts in mitochondrial free radical production. An increase in intraerythrocytic reduced glutathione (GSH) during deoxygenation would support the detoxification of exogenous oxidants released into the circulation from hypoxic peripher...

Descripción completa

Detalles Bibliográficos
Autores principales: Fenk, Simone, Melnikova, Elizaveta V., Anashkina, Anastasia A., Poluektov, Yuri M., Zaripov, Pavel I., Mitkevich, Vladimir A., Tkachev, Yaroslav V., Kaestner, Lars, Minetti, Giampaolo, Mairbäurl, Heimo, Goede, Jeroen S., Makarov, Alexander A., Petrushanko, Irina Yu, Bogdanova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679038/
https://www.ncbi.nlm.nih.gov/pubmed/36413919
http://dx.doi.org/10.1016/j.redox.2022.102535