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Hemoglobin is an oxygen-dependent glutathione buffer adapting the intracellular reduced glutathione levels to oxygen availability
Fast changes in environmental oxygen availability translate into shifts in mitochondrial free radical production. An increase in intraerythrocytic reduced glutathione (GSH) during deoxygenation would support the detoxification of exogenous oxidants released into the circulation from hypoxic peripher...
Autores principales: | Fenk, Simone, Melnikova, Elizaveta V., Anashkina, Anastasia A., Poluektov, Yuri M., Zaripov, Pavel I., Mitkevich, Vladimir A., Tkachev, Yaroslav V., Kaestner, Lars, Minetti, Giampaolo, Mairbäurl, Heimo, Goede, Jeroen S., Makarov, Alexander A., Petrushanko, Irina Yu, Bogdanova, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679038/ https://www.ncbi.nlm.nih.gov/pubmed/36413919 http://dx.doi.org/10.1016/j.redox.2022.102535 |
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