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Reprogrammed fecal and mucosa-associated intestinal microbiota and weakened mucus layer in intestinal goblet cell- specific Piezo1-deficient mice

Dysfunction of the mucus layer allows commensal and pathogenic microorganisms to reach the intestinal epithelium, thereby leading to infection and inflammation. This barrier is synthesized and secreted by host goblet cells. Many factors that influence the function of goblet cells (GCs) have been stu...

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Detalles Bibliográficos
Autores principales: Liu, Ying, Fang, Feifei, Xiong, Yilin, Wu, Jiandi, Li, Xueyan, Li, Gangping, Bai, Tao, Hou, Xiaohua, Song, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679152/
https://www.ncbi.nlm.nih.gov/pubmed/36425784
http://dx.doi.org/10.3389/fcimb.2022.1035386