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Neurofilament light-associated connectivity in young-adult Huntington’s disease is related to neuronal genes

Upregulation of functional network connectivity in the presence of structural degeneration is seen in the premanifest stages of Huntington’s disease (preHD) 10–15 years from clinical diagnosis. However, whether widespread network connectivity changes are seen in gene carriers much further from onset...

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Detalles Bibliográficos
Autores principales: McColgan, Peter, Gregory, Sarah, Zeun, Paul, Zarkali, Angeliki, Johnson, Eileanoir B, Parker, Christopher, Fayer, Kate, Lowe, Jessica, Nair, Akshay, Estevez-Fraga, Carlos, Papoutsi, Marina, Zhang, Hui, Scahill, Rachael I, Tabrizi, Sarah J, Rees, Geraint
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679168/
https://www.ncbi.nlm.nih.gov/pubmed/35758263
http://dx.doi.org/10.1093/brain/awac227