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Amyloid-β levels and cognitive trajectories in non-demented pTau181-positive subjects without amyloidopathy

Phosphorylated Tau181 (pTau181) in CSF and recently in plasma has been associated with Alzheimer’s disease. In the absence of amyloidopathy, individuals with increased total Tau levels and/or temporal lobe atrophy experience no or only mild cognitive decline compared with biomarker-negative controls...

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Detalles Bibliográficos
Autores principales: Oberstein, Timo Jan, Schmidt, Manuel Alexander, Florvaag, Anna, Haas, Anna-Lena, Siegmann, Eva-Maria, Olm, Pauline, Utz, Janine, Spitzer, Philipp, Doerfler, Arnd, Lewczuk, Piotr, Kornhuber, Johannes, Maler, Juan Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679169/
https://www.ncbi.nlm.nih.gov/pubmed/35973034
http://dx.doi.org/10.1093/brain/awac297