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Amyloid-β levels and cognitive trajectories in non-demented pTau181-positive subjects without amyloidopathy
Phosphorylated Tau181 (pTau181) in CSF and recently in plasma has been associated with Alzheimer’s disease. In the absence of amyloidopathy, individuals with increased total Tau levels and/or temporal lobe atrophy experience no or only mild cognitive decline compared with biomarker-negative controls...
Autores principales: | Oberstein, Timo Jan, Schmidt, Manuel Alexander, Florvaag, Anna, Haas, Anna-Lena, Siegmann, Eva-Maria, Olm, Pauline, Utz, Janine, Spitzer, Philipp, Doerfler, Arnd, Lewczuk, Piotr, Kornhuber, Johannes, Maler, Juan Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679169/ https://www.ncbi.nlm.nih.gov/pubmed/35973034 http://dx.doi.org/10.1093/brain/awac297 |
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