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Immunoglobulin G N-Glycosylation Signatures in Incident Type 2 Diabetes and Cardiovascular Disease

OBJECTIVE: N-glycosylation is a functional posttranslational modification of immunoglobulins (Igs). We hypothesized that specific IgG N-glycans are associated with incident type 2 diabetes and cardiovascular disease (CVD). RESEARCH DESIGN AND METHODS: We performed case-cohort studies within the popu...

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Detalles Bibliográficos
Autores principales: Birukov, Anna, Plavša, Branimir, Eichelmann, Fabian, Kuxhaus, Olga, Hoshi, Rosangela Akemi, Rudman, Najda, Štambuk, Tamara, Trbojević-Akmačić, Irena, Schiborn, Catarina, Morze, Jakub, Mihelčić, Matea, Cindrić, Ana, Liu, Yanyan, Demler, Olga, Perola, Markus, Mora, Samia, Schulze, Matthias B., Lauc, Gordan, Wittenbecher, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679264/
https://www.ncbi.nlm.nih.gov/pubmed/36174116
http://dx.doi.org/10.2337/dc22-0833