The βI domain promotes active β1 integrin clustering into mature adhesion sites

Modulation of integrin function is required in many physiological and pathological settings, such as angiogenesis and cancer. Integrin allosteric changes, clustering, and trafficking cooperate to regulate cell adhesion and motility on extracellular matrix proteins via mechanisms that are partly defi...

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Detalles Bibliográficos
Autores principales: Mana, Giulia, Valdembri, Donatella, Askari, Janet A, Li, Zhenhai, Caswell, Patrick, Zhu, Cheng, Humphries, Martin J, Ballestrem, Christoph, Serini, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679427/
https://www.ncbi.nlm.nih.gov/pubmed/36410791
http://dx.doi.org/10.26508/lsa.202201388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679427/
https://www.ncbi.nlm.nih.gov/pubmed/36410791
http://dx.doi.org/10.26508/lsa.202201388

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