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Usnic Acid extends healthspan and improves the neurodegeneration diseases via mTOR/PHA-4 signaling pathway in Caenorhabditis elegans

The Mammalian/mechanistic target of rapamycin (mTOR) played a central role in cellular survival and aging. Inhibition of mTOR had been proposed as a reasonable strategy to promote lifespan and delay age-related diseases in evolutionarily diverse organisms. The study showed that lifespan extension an...

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Detalles Bibliográficos
Autores principales: Xiao, Yi, Zhang, Huiling, Sheng, Yi, Liu, Fang, Gao, Jiajun, Liu, Guosheng, Li, Sanhua, Jiang, Nian, Yu, Changyan, Liu, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679492/
https://www.ncbi.nlm.nih.gov/pubmed/36425761
http://dx.doi.org/10.1016/j.isci.2022.105539