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Usnic Acid extends healthspan and improves the neurodegeneration diseases via mTOR/PHA-4 signaling pathway in Caenorhabditis elegans
The Mammalian/mechanistic target of rapamycin (mTOR) played a central role in cellular survival and aging. Inhibition of mTOR had been proposed as a reasonable strategy to promote lifespan and delay age-related diseases in evolutionarily diverse organisms. The study showed that lifespan extension an...
Autores principales: | Xiao, Yi, Zhang, Huiling, Sheng, Yi, Liu, Fang, Gao, Jiajun, Liu, Guosheng, Li, Sanhua, Jiang, Nian, Yu, Changyan, Liu, Yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679492/ https://www.ncbi.nlm.nih.gov/pubmed/36425761 http://dx.doi.org/10.1016/j.isci.2022.105539 |
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