Benchmarking freely available HLA typing algorithms across varying genes, coverages and typing resolutions

Identifying the specific human leukocyte antigen (HLA) allele combination of an individual is crucial in organ donation, risk assessment of autoimmune and infectious diseases and cancer immunotherapy. However, due to the high genetic polymorphism in this region, HLA typing requires specialized metho...

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Detalles Bibliográficos
Autores principales: Thuesen, Nikolas Hallberg, Klausen, Michael Schantz, Gopalakrishnan, Shyam, Trolle, Thomas, Renaud, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679531/
https://www.ncbi.nlm.nih.gov/pubmed/36426357
http://dx.doi.org/10.3389/fimmu.2022.987655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679531/
https://www.ncbi.nlm.nih.gov/pubmed/36426357
http://dx.doi.org/10.3389/fimmu.2022.987655

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