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Benchmarking freely available HLA typing algorithms across varying genes, coverages and typing resolutions
Identifying the specific human leukocyte antigen (HLA) allele combination of an individual is crucial in organ donation, risk assessment of autoimmune and infectious diseases and cancer immunotherapy. However, due to the high genetic polymorphism in this region, HLA typing requires specialized metho...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679531/ https://www.ncbi.nlm.nih.gov/pubmed/36426357 http://dx.doi.org/10.3389/fimmu.2022.987655 |