Salvianolic acid A regulates pyroptosis of endothelial cells via directly targeting PKM2 and ameliorates diabetic atherosclerosis

Rescuing endothelial cells from pyroptotic cell death emerges as a potential therapeutic strategy to combat diabetic atherosclerosis. Salvianolic acid A (SAA) is a major water-soluble phenolic acid in the Salvia miltiorrhiza Bunge, which has been used in traditional Chinese medicine (TCM) and health...

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Detalles Bibliográficos
Autores principales: Zhu, Ji, Chen, Hang, Le, Yifei, Guo, Jianan, Liu, Zhijun, Dou, Xiaobing, Lu, Dezhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679534/
https://www.ncbi.nlm.nih.gov/pubmed/36425580
http://dx.doi.org/10.3389/fphar.2022.1009229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679534/
https://www.ncbi.nlm.nih.gov/pubmed/36425580
http://dx.doi.org/10.3389/fphar.2022.1009229

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