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Salvianolic acid A regulates pyroptosis of endothelial cells via directly targeting PKM2 and ameliorates diabetic atherosclerosis
Rescuing endothelial cells from pyroptotic cell death emerges as a potential therapeutic strategy to combat diabetic atherosclerosis. Salvianolic acid A (SAA) is a major water-soluble phenolic acid in the Salvia miltiorrhiza Bunge, which has been used in traditional Chinese medicine (TCM) and health...
Autores principales: | Zhu, Ji, Chen, Hang, Le, Yifei, Guo, Jianan, Liu, Zhijun, Dou, Xiaobing, Lu, Dezhao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679534/ https://www.ncbi.nlm.nih.gov/pubmed/36425580 http://dx.doi.org/10.3389/fphar.2022.1009229 |
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