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ER stress and calcium-dependent arrhythmias
The sarcoplasmic reticulum (SR) plays the key role in cardiac function as the major source of Ca(2+) that activates cardiomyocyte contractile machinery. Disturbances in finely-tuned SR Ca(2+) release by SR Ca(2+) channel ryanodine receptor (RyR2) and SR Ca(2+) reuptake by SR Ca(2+)-ATPase (SERCa2a)...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679650/ https://www.ncbi.nlm.nih.gov/pubmed/36425292 http://dx.doi.org/10.3389/fphys.2022.1041940 |