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Contemporary biophysical approaches for studying 14-3-3 protein-protein interactions

14-3-3 proteins are a family of regulatory hubs that function through a vast network of protein-protein interactions. Their dysfunction or dysregulation is implicated in a wide range of diseases, and thus they are attractive drug targets, especially for molecular glues that promote protein-protein i...

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Detalles Bibliográficos
Autores principales: Thurairajah, Bethany, Hudson, Andrew J., Doveston, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679655/
https://www.ncbi.nlm.nih.gov/pubmed/36425654
http://dx.doi.org/10.3389/fmolb.2022.1043673