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Paramagnetic rims are a promising diagnostic imaging biomarker in multiple sclerosis

BACKGROUND: White matter lesions (WMLs) on brain magnetic resonance imaging (MRI) in multiple sclerosis (MS) may contribute to misdiagnosis. In chronic active lesions, peripheral iron-laden macrophages appear as paramagnetic rim lesions (PRLs). OBJECTIVE: To evaluate the sensitivity and specificity...

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Detalles Bibliográficos
Autores principales: Meaton, Isobel, Altokhis, Amjad, Allen, Christopher Martin, Clarke, Margareta A, Sinnecker, Tim, Meier, Dominik, Enzinger, Christian, Calabrese, Massimiliano, De Stefano, Nicola, Pitiot, Alain, Giorgio, Antonio, Schoonheim, Menno M, Paul, Friedemann, Pawlak, Mikolaj A, Schmidt, Reinhold, Granziera, Cristina, Kappos, Ludwig, Montalban, Xavier, Rovira, Àlex, Wuerfel, Jens, Evangelou, Nikos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679799/
https://www.ncbi.nlm.nih.gov/pubmed/36017870
http://dx.doi.org/10.1177/13524585221118677