Learning deep representations of enzyme thermal adaptation

Temperature is a fundamental environmental factor that shapes the evolution of organisms. Learning thermal determinants of protein sequences in evolution thus has profound significance for basic biology, drug discovery, and protein engineering. Here, we use a data set of over 3 million BRENDA enzyme...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Gang, Buric, Filip, Zrimec, Jan, Viknander, Sandra, Nielsen, Jens, Zelezniak, Aleksej, Engqvist, Martin K. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Methods and Applications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679980/
https://www.ncbi.nlm.nih.gov/pubmed/36261883
http://dx.doi.org/10.1002/pro.4480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679980/
https://www.ncbi.nlm.nih.gov/pubmed/36261883
http://dx.doi.org/10.1002/pro.4480

Ejemplares similares