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Scale-Up of a Rh-Catalyzed Asymmetric sp(3)–sp(2) Suzuki–Miyaura-Type Reaction

[Image: see text] Csp(2)–Csp(2) Suzuki–Miyaura couplings (SMCs) are ubiquitous in the synthesis of small molecules, but analogous Csp(2)–Csp(3) bond-forming SMCs are rare, especially asymmetric variants. Recently, we developed a series of Rh-catalyzed couplings between racemic sp(3)-hybridized allyl...

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Detalles Bibliográficos
Autores principales: Cunningham, Laura, Portela, Mireia Sidera, Fletcher, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680029/
https://www.ncbi.nlm.nih.gov/pubmed/36437898
http://dx.doi.org/10.1021/acs.oprd.2c00268