Conformationally Locked Carbocyclic Nucleosides Built on a 4′-Hydroxymethyl-3′-hydroxybicyclo[4.1.0]heptane Template. Stereoselective Synthesis and Antiviral Activity

[Image: see text] Two new families of enantiomerically pure carbocyclic nucleoside analogues based on a cyclohexane moiety with five chiral centers and a fused cyclopropyl ring have been synthesized. A highly regio- and stereoselective synthetic approach for the modular construction of the functiona...

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Detalles Bibliográficos
Autores principales: Jurado, Sergio, Illa, Ona, Álvarez-Larena, Angel, Pannecouque, Christophe, Busqué, Félix, Alibés, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680032/
https://www.ncbi.nlm.nih.gov/pubmed/36300902
http://dx.doi.org/10.1021/acs.joc.2c01661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680032/
https://www.ncbi.nlm.nih.gov/pubmed/36300902
http://dx.doi.org/10.1021/acs.joc.2c01661

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