Complete abrogation of key osteoclast markers with a membrane-anchored tissue inhibitor of metalloproteinase: a novel approach in the prevention of osteoclastogenesis

AIMS: Tissue inhibitors of metalloproteinases (TIMPs) are the endogenous inhibitors of the zinc-dependent matrix metalloproteinases (MMP) and A disintegrin and metalloproteinases (ADAM) involved in extracellular matrix modulation. The present study aims to develop the TIMPs as biologics for osteocla...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yihe, Jiang, Bingjie, Zhang, Pengyuan, Chiu, Sung K., Lee, Meng H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2022
Materias:
Bone Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680204/
https://www.ncbi.nlm.nih.gov/pubmed/36331083
http://dx.doi.org/10.1302/2046-3758.1111.BJR-2022-0147.R2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680204/
https://www.ncbi.nlm.nih.gov/pubmed/36331083
http://dx.doi.org/10.1302/2046-3758.1111.BJR-2022-0147.R2

Ejemplares similares