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Complete abrogation of key osteoclast markers with a membrane-anchored tissue inhibitor of metalloproteinase: a novel approach in the prevention of osteoclastogenesis

AIMS: Tissue inhibitors of metalloproteinases (TIMPs) are the endogenous inhibitors of the zinc-dependent matrix metalloproteinases (MMP) and A disintegrin and metalloproteinases (ADAM) involved in extracellular matrix modulation. The present study aims to develop the TIMPs as biologics for osteocla...

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Detalles Bibliográficos
Autores principales:	Zhang, Yihe, Jiang, Bingjie, Zhang, Pengyuan, Chiu, Sung K., Lee, Meng H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The British Editorial Society of Bone & Joint Surgery 2022
Materias:	Bone Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680204/ https://www.ncbi.nlm.nih.gov/pubmed/36331083 http://dx.doi.org/10.1302/2046-3758.1111.BJR-2022-0147.R2

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