Extended local release and improved bacterial eradication by adding rifampicin to a biphasic ceramic carrier containing gentamicin or vancomycin

AIMS: There is a lack of biomaterial-based carriers for the local delivery of rifampicin (RIF), one of the cornerstone second defence antibiotics for bone infections. RIF is also known for causing rapid development of antibiotic resistance when given as monotherapy. This in vitro study evaluated a c...

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Detalles Bibliográficos
Autores principales: Sebastian, Sujeesh, Tandberg, Felix, Liu, Yang, Raina, Deepak B., Tägil, Magnus, Collin, Mattias, Lidgren, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2022
Materias:
Biomaterials
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680205/
https://www.ncbi.nlm.nih.gov/pubmed/36349950
http://dx.doi.org/10.1302/2046-3758.1111.BJR-2022-0101.R1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680205/
https://www.ncbi.nlm.nih.gov/pubmed/36349950
http://dx.doi.org/10.1302/2046-3758.1111.BJR-2022-0101.R1

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