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Appropriate Amounts and Activity of the Wilms’ Tumor Suppressor Gene, wt1, Are Required for Normal Pronephros Development of Xenopus Embryos

The Wilms’ tumor suppressor gene, wt1, encodes a zinc finger-containing transcription factor that binds to a GC-rich motif and regulates the transcription of target genes. wt1 was first identified as a tumor suppressor gene in Wilms’ tumor, a pediatric kidney tumor, and has been implicated in normal...

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Detalles Bibliográficos
Autores principales: Shiraki, Taisei, Hayashi, Takuma, Ozue, Jotaro, Watanabe, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680428/
https://www.ncbi.nlm.nih.gov/pubmed/36412640
http://dx.doi.org/10.3390/jdb10040046