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Pan HDACi Valproic Acid and Trichostatin A Show Apparently Contrasting Inflammatory Responses in Cultured J774A.1 Macrophages

This study was initiated as an attempt to clarify some of the apparent conflicting data regarding the so-called anti-inflammatory versus proinflammatory properties of histone deacetylase inhibitors (HDACis). In cell culture, typically, chronic pretreatment with the HDACi valproic acid (VPA) and tric...

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Detalles Bibliográficos
Autores principales: Ubah, Ubah Dominic Babah, Triyasakorn, Korawin, Roan, Brandon, Conlin, Minsyusheen, Lai, James C. K., Awale, Prabha S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680436/
https://www.ncbi.nlm.nih.gov/pubmed/36412793
http://dx.doi.org/10.3390/epigenomes6040038