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Regulation of Polyhomeotic Condensates by Intrinsically Disordered Sequences That Affect Chromatin Binding

The Polycomb group (PcG) complex PRC1 localizes in the nucleus in condensed structures called Polycomb bodies. The PRC1 subunit Polyhomeotic (Ph) contains an oligomerizing sterile alpha motif (SAM) that is implicated in both PcG body formation and chromatin organization in Drosophila and mammalian c...

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Detalles Bibliográficos
Autores principales: Kapur, Ibani, Boulier, Elodie L., Francis, Nicole J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680516/
https://www.ncbi.nlm.nih.gov/pubmed/36412795
http://dx.doi.org/10.3390/epigenomes6040040