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The concentration-dependent effect of hydrocortisone on the structure of model lung surfactant monolayer by using an in silico approach

Understanding the adsorption mechanism of corticosteroids in the lung surfactant requires the knowledge of corticosteroid molecular interactions with lung surfactant monolayer (LSM). We employed coarse-grained molecular dynamics simulation to explore the action of hydrocortisone on an LSM comprised...

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Detalles Bibliográficos
Autores principales: Islam, Mohammad Zohurul, Hossain, Sheikh I., Deplazes, E., Luo, Zhen, Saha, Suvash C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680622/
https://www.ncbi.nlm.nih.gov/pubmed/36506480
http://dx.doi.org/10.1039/d2ra05268g