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Design, synthesis, and biological evaluation of novel bioactive thalidomide analogs as anticancer immunomodulatory agents

Cancer is still a dangerous disease with a high mortality rate all over the world. In our attempt to develop potential anticancer candidates, new quinazoline and phthalazine based compounds were designed and synthesized. The new derivatives were built in line with the pharmacophoric features of thal...

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Detalles Bibliográficos
Autores principales: Kotb, Anas Ramadan, Bakhotmah, Dina A., Abdallah, Abdallah E., Elkady, Hazem, Taghour, Mohammed S., Eissa, Ibrahim. H., El-Zahabi, Mohamed Ayman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680624/
https://www.ncbi.nlm.nih.gov/pubmed/36505721
http://dx.doi.org/10.1039/d2ra06188k