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Design, synthesis, and biological evaluation of novel bioactive thalidomide analogs as anticancer immunomodulatory agents

Cancer is still a dangerous disease with a high mortality rate all over the world. In our attempt to develop potential anticancer candidates, new quinazoline and phthalazine based compounds were designed and synthesized. The new derivatives were built in line with the pharmacophoric features of thal...

Полное описание

Библиографические подробности
Главные авторы: Kotb, Anas Ramadan, Bakhotmah, Dina A., Abdallah, Abdallah E., Elkady, Hazem, Taghour, Mohammed S., Eissa, Ibrahim. H., El-Zahabi, Mohamed Ayman
Формат: Online Статья Текст
Язык:English
Опубликовано: The Royal Society of Chemistry 2022
Предметы:
Online-ссылка:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680624/
https://www.ncbi.nlm.nih.gov/pubmed/36505721
http://dx.doi.org/10.1039/d2ra06188k