Performance of polygenic risk scores for cancer prediction in a racially diverse academic biobank

PURPOSE: Genome-wide association studies have identified hundreds of single nucleotide variations (formerly single nucleotide polymorphisms) associated with several cancers, but the predictive ability of polygenic risk scores (PRSs) is unclear, especially among non-Whites. METHODS: PRSs were derived...

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Detalles Bibliográficos
Autores principales: Wang, Louise, Desai, Heena, Verma, Shefali S., Le, Anh, Hausler, Ryan, Verma, Anurag, Judy, Renae, Doucette, Abigail, Gabriel, Peter E., Nathanson, Katherine L., Damrauer, Scott M., Mowery, Danielle L., Ritchie, Marylyn D., Kember, Rachel L., Maxwell, Kara N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680700/
https://www.ncbi.nlm.nih.gov/pubmed/34906489
http://dx.doi.org/10.1016/j.gim.2021.10.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680700/
https://www.ncbi.nlm.nih.gov/pubmed/34906489
http://dx.doi.org/10.1016/j.gim.2021.10.015

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