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A trafficking motif alters GEVI activity implicating persistent protein interactions at the membrane

Efficient plasma-membrane expression is critical for genetically encoded voltage indicators (GEVIs). To improve the plasma-membrane expression, we introduced multiple combinations of plasma-membrane trafficking motifs at different positions to members of the Bongwoori family of GEVIs. An improvement...

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Detalles Bibliográficos
Autores principales: Lee, Sungmoo, Kang, Bok Eum, Song, Yoon-Kyu, Baker, Bradley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680705/
https://www.ncbi.nlm.nih.gov/pubmed/36425771
http://dx.doi.org/10.1016/j.bpr.2022.100047