Diagnosing and mitigating method-based avidity artifacts that confound polyubiquitin-binding assays

Polyubiquitination is a complex form of posttranslational modification responsible for the control of numerous cellular processes. Many ubiquitin-binding proteins recognize distinct polyubiquitin chain types, and these associations help drive ubiquitin-signaling pathways. There is considerable inter...

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Detalles Bibliográficos
Autores principales: Schoeffler, Allyn J., Helgason, Elizabeth, Popovych, Nataliya, Dueber, Erin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680732/
https://www.ncbi.nlm.nih.gov/pubmed/36425458
http://dx.doi.org/10.1016/j.bpr.2021.100033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680732/
https://www.ncbi.nlm.nih.gov/pubmed/36425458
http://dx.doi.org/10.1016/j.bpr.2021.100033

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