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Diagnosing and mitigating method-based avidity artifacts that confound polyubiquitin-binding assays
Polyubiquitination is a complex form of posttranslational modification responsible for the control of numerous cellular processes. Many ubiquitin-binding proteins recognize distinct polyubiquitin chain types, and these associations help drive ubiquitin-signaling pathways. There is considerable inter...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680732/ https://www.ncbi.nlm.nih.gov/pubmed/36425458 http://dx.doi.org/10.1016/j.bpr.2021.100033 |