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Transport between im/mobile fractions shapes the speed and profile of cargo distribution in neurons

Neuronal function requires continuous distribution of ion channels and other proteins throughout large cell morphologies. Protein distribution is complicated by immobilization of freely diffusing subunits such as on lipid rafts or in postsynaptic densities. Here, we infer rates of immobilization for...

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Detalles Bibliográficos
Autores principales: Bellotti, Adriano A., Murphy, Jonathan G., O’Leary, Timothy S., Hoffman, Dax A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680811/
https://www.ncbi.nlm.nih.gov/pubmed/36425667
http://dx.doi.org/10.1016/j.bpr.2022.100082