A pyridinesulfonamide derivative FD268 suppresses cell proliferation and induces apoptosis via inhibiting PI3K pathway in acute myeloid leukemia

Aberration of PI3K signaling pathway has been confirmed to be associated with several hematological malignancies including acute myeloid leukemia (AML). FD268, a pyridinesulfonamide derivative characterized by the conjugation of 7-azaindole group, is a newly identified PI3K inhibitor showing high po...

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Detalles Bibliográficos
Autores principales: Chen, Yi, Wu, Tianze, Yang, Chengbin, Lu, Mingzhu, Chen, Zhenxia, Deng, Mingli, Jia, Yu, Yang, Yongtai, Liu, Xiaofeng, Wang, Hongyan, Ling, Yun, Lu, Lei, Zhou, Yaming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681083/
https://www.ncbi.nlm.nih.gov/pubmed/36413544
http://dx.doi.org/10.1371/journal.pone.0277893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681083/
https://www.ncbi.nlm.nih.gov/pubmed/36413544
http://dx.doi.org/10.1371/journal.pone.0277893

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