Cargando…

A pyridinesulfonamide derivative FD268 suppresses cell proliferation and induces apoptosis via inhibiting PI3K pathway in acute myeloid leukemia

Aberration of PI3K signaling pathway has been confirmed to be associated with several hematological malignancies including acute myeloid leukemia (AML). FD268, a pyridinesulfonamide derivative characterized by the conjugation of 7-azaindole group, is a newly identified PI3K inhibitor showing high po...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Yi, Wu, Tianze, Yang, Chengbin, Lu, Mingzhu, Chen, Zhenxia, Deng, Mingli, Jia, Yu, Yang, Yongtai, Liu, Xiaofeng, Wang, Hongyan, Ling, Yun, Lu, Lei, Zhou, Yaming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681083/ https://www.ncbi.nlm.nih.gov/pubmed/36413544 http://dx.doi.org/10.1371/journal.pone.0277893

Ejemplares similares

Hollow carbon nanospheres embedded with stoichiometric γ-Fe(2)O(3) and GdPO(4): tuning the nanospheres for in vitro and in vivo size effect evaluation
por: Zhang, Hui, et al.
Publicado: (2022)

Health Tract, No. 268: Adulterations
Publicado: (1867)

FD&C Yellow No. 6
Publicado: (1982)

An Introduction of FD-Complete Constraints
por: Löffler, Sven, et al.
Publicado: (2020)

Ectopic expression of Arabidopsis FD and FD PARALOGUE in rice results in dwarfism with size reduction of spikelets
por: Jang, Seonghoe, et al.
Publicado: (2017)

Role of the Forkhead Transcription Factors Fd4 and Fd5 During Drosophila Leg Development
por: Ruiz-Losada, Mireya, et al.
Publicado: (2021)

Effects of LG268 on Cell Proliferation and Apoptosis of NB4 Cells
por: Xu, Ting, et al.
Publicado: (2016)

268 Nonuremic Calciphylaxis—A Rare Case
Publicado: (2020)

Anatomy of $F_D$-Term Hybrid Inflation
por: Garbrecht, Bjorn, et al.
Publicado: (2006)

Acute Myeloid Leukemia Masquerading as Acute Appendicitis
por: Shen, Kai, et al.
Publicado: (2017)

Recognition memory reconsolidation requires hippocampal Zif268
por: Gonzalez, Maria Carolina, et al.
Publicado: (2019)

I. Verzeichnis der in Band 268 enthaltenen Arbeiten
Publicado: (1988)

Filamentous Bacteriophage Fd as an Antigen Delivery System in Vaccination
por: Prisco, Antonella, et al.
Publicado: (2012)

Stereoacuity with Frisby and Revised FD2 Stereo Tests
por: Bohr, Iwo, et al.
Publicado: (2013)

Their C-termini divide Brassica rapa FT-like proteins into FD-interacting and FD-independent proteins that have different effects on the floral transition
por: Lee, Areum, et al.
Publicado: (2023)

Security-Related Hardware Cost Optimization for CAN FD-Based Automotive Cyber-Physical Systems
por: Xie, Yong, et al.
Publicado: (2021)

Evaluation of Serum 25‐Hydroxyvitamin D(3) and Bone Mineral Density in 268 Patients with Hip Fractures
por: Yu, Shu‐jun, et al.
Publicado: (2021)

LightFD: Real-Time Fault Diagnosis with Edge Intelligence for Power Transformers
por: Fu, Xinhua, et al.
Publicado: (2022)

Genome Sequence of Salmonella bongori Strain N268-08
por: Marti, Roger, et al.
Publicado: (2013)

TERMINAL FLOWER 1-FD complex target genes and competition with FLOWERING LOCUS T
por: Zhu, Yang, et al.
Publicado: (2020)

In situ embedding dual-Fe nanoparticles in synchronously generated carbon for the synergistic integration of magnetic resonance imaging and drug delivery
por: Zhang, Hui, et al.
Publicado: (2020)

P617: FIXED-DURATION (FD) IBRUTINIB + VENETOCLAX FOR FIRST-LINE TREATMENT OF CHRONIC LYMPHOCYTIC LEUKEMIA (CLL)/SMALL LYMPHOCYTIC LYMPHOMA (SLL): 4-Y FOLLOW-UP FROM FD COHORT OF PHASE 2 CAPTIVATE STUDY
por: Ghia, Paolo, et al.
Publicado: (2023)

Plasmacytoid Dendritic Cells Proliferation Coexisted with Acute Myeloid Leukemia
por: Wang, Min, et al.
Publicado: (2018)

Physics Simulations of fluids - a brief overview of Phoenix FD
por: Iliev, Ivaylo, et al.
Publicado: (2014)

SCALEUS-FD: A FAIR Data Tool for Biomedical Applications
por: Pereira, Arnaldo, et al.
Publicado: (2020)

BrainFD: Measuring the Intracranial Brain Volume With Fractal Dimension
por: Ashraf, Ghulam Md, et al.
Publicado: (2021)

Recent Progress in FD-LC-MS/MS Proteomics Method
por: Kobayashi, Hiroshi, et al.
Publicado: (2021)

Notch2 inhibits proliferation of chronic myeloid leukemia cells
por: YANG, ZESONG, et al.
Publicado: (2013)

High expression of COMMD7 is an adverse prognostic factor in acute myeloid leukemia
por: Li, Kongfei, et al.
Publicado: (2021)

Dataset of FD&C Certified Food Dyes in Foods Commonly Consumed by Children
por: Lehmkuhler, Arlie L., et al.
Publicado: (2022)

Quantification of Venetoclax for Therapeutic Drug Monitoring in Chinese Acute Myeloid Leukemia Patients by a Validated UPLC-MS/MS Method
por: Yang, Xi, et al.
Publicado: (2022)

Targeting Approaches of Nanomedicines in Acute Myeloid Leukemia
por: Huang, Xiao, et al.
Publicado: (2019)

Downregulation of SMIM3 inhibits growth of leukemia via PI3K-AKT signaling pathway and correlates with prognosis of adult acute myeloid leukemia with normal karyotype
por: Liu, Yu, et al.
Publicado: (2022)

HIPK2 Phosphorylates the Microtubule-Severing Enzyme Spastin at S268 for Abscission
por: Pisciottani, Alessandra, et al.
Publicado: (2019)

MON-268 A Rare Case of Primary Hypoaldosteronism in a Newborn
por: Mody, Armaiti, et al.
Publicado: (2019)

Parosmia Due to COVID-19 Disease: A 268 Case Series
por: Rashid, Rasheed Ali, et al.
Publicado: (2021)

P268 Laryngeal Mucormycosis: does mucor take the voice away?
por: Rege, Sujata, et al.
Publicado: (2022)

FRI268 Late Onset Polyglandular Autoimmune Syndrome Type 2
por: Nicholson, Matthew S, et al.
Publicado: (2023)

EPAC null mutation impairs learning and social interactions via aberrant regulation of miR-124 and Zif268 translation
por: Yang, Ying, et al.
Publicado: (2012)

Corneal Sublayers Thickness Estimation Obtained by High-Resolution FD-OCT
por: Alberto, Diego, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_o0dtu4vot0snp2hsthvn9tkhcn