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Simultaneous depletion of RB, RBL1 and RBL2 affects endoderm differentiation of human embryonic stem cells

RB is a well-known cell cycle regulator controlling the G1 checkpoint. Previous reports have suggested that it can influence cell fate decisions not only by regulating cell proliferation and survival but also by interacting with transcription factors and epigenetic modifiers. However, the functional...

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Detalles Bibliográficos
Autores principales: Nakanoh, Shota, Kadiwala, Juned, Pinte, Laetitia, Morell, Carola Maria, Lenaerts, An-Sofie, Vallier, Ludovic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681086/
https://www.ncbi.nlm.nih.gov/pubmed/36413521
http://dx.doi.org/10.1371/journal.pone.0269122