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Oropharyngeal tumor cells induce COX-2 expression in peripheral blood monocytes by secretion of IL-1α

Oropharyngeal squamous cell cancer (OPC) accounts for 3% of all cancers and greater than 1.5% of all cancer deaths in the United States, with marked treatment-associated morbidity in survivors. More than 80% of OPC is caused by HPV16. Tumors induced by HPV have been linked to impaired immune functio...

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Detalles Bibliográficos
Autores principales: DeVoti, James A., Israr, Mohd, Lam, Fung, Papayannakos, Christopher, Frank, Douglas K., Kamdar, Dev P., Pereira, Lucio M., Abramson, Allan, Steinberg, Bettie M., Bonagura, Vincent R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681149/
https://www.ncbi.nlm.nih.gov/pubmed/36426368
http://dx.doi.org/10.3389/fimmu.2022.1011772