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Mcm2 promotes stem cell differentiation via its ability to bind H3-H4

Mcm2, a subunit of the minichromosome maintenance proteins 2–7 (Mcm2-7) helicase best known for its role in DNA replication, contains a histone binding motif that facilitates the transfer of parental histones following DNA replication. Here, we show that Mcm2 is important for the differentiation of...

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Detalles Bibliográficos
Autores principales: Xu, Xiaowei, Hua, Xu, Brown, Kyle, Ren, Xiaojun, Zhang, Zhiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681210/
https://www.ncbi.nlm.nih.gov/pubmed/36354740
http://dx.doi.org/10.7554/eLife.80917