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Mechanisms governing target search and binding dynamics of hypoxia-inducible factors

Transcription factors (TFs) are classically attributed a modular construction, containing well-structured sequence-specific DNA-binding domains (DBDs) paired with disordered activation domains (ADs) responsible for protein-protein interactions targeting co-factors or the core transcription initiatio...

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Detalles Bibliográficos
Autores principales: Chen, Yu, Cattoglio, Claudia, Dailey, Gina M, Zhu, Qiulin, Tjian, Robert, Darzacq, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681212/
https://www.ncbi.nlm.nih.gov/pubmed/36322456
http://dx.doi.org/10.7554/eLife.75064