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Various Application of Tofacitinib and Ruxolitinib (Janus Kinase Inhibitors) in Dermatology and Rheumatology: A Review of Current Evidence and Future Perspective
INTRODUCTION: Janus kinase inhibitors (JAKi) are anti-inflammatory medications suppressing Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway by inhibiting various cytokines receptors on the membrane of cells. Mutations and polymorphisms on JAK and STAT proteins can cau...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mattioli 1885
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681403/ https://www.ncbi.nlm.nih.gov/pubmed/36534552 http://dx.doi.org/10.5826/dpc.1204a178 |