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Regulation of the apoptosis/autophagy switch by propionic acid in ventromedial hypothalamus of rats with type 2 diabetes mellitus

BACKGROUND: Hypothalamic dysregulation may cause abnormal glucose metabolism and type 2 diabetes mellitus (T2DM). The balance between autophagy and apoptosis is important for maintaining cellular/tissue homeostasis and may be disrupted in T2DM. OBJECTIVES: Since propionic acid (PA) exerts neuroprote...

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Detalles Bibliográficos
Autores principales: Natrus, Larysa, Osadchuk, Yuliia, Lisakovska, Olha, Roch, Toralf, Babel, Nina, Klys, Yuliia, Labudzynskyi, Dmytro, Chaikovsky, Yuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681650/
https://www.ncbi.nlm.nih.gov/pubmed/36439719
http://dx.doi.org/10.1016/j.heliyon.2022.e11529