Alveolar cell fate selection and lifelong maintenance of AT2 cells by FGF signaling

The lung’s gas exchange surface is comprised of alveolar AT1 and AT2 cells that are corrupted in several common and deadly diseases. They arise from a bipotent progenitor whose differentiation is thought to be dictated by differential mechanical forces. Here we show the critical determinant is FGF s...

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Detalles Bibliográficos
Autores principales: Brownfield, Douglas G., de Arce, Alex Diaz, Ghelfi, Elisa, Gillich, Astrid, Desai, Tushar J., Krasnow, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681748/
https://www.ncbi.nlm.nih.gov/pubmed/36414616
http://dx.doi.org/10.1038/s41467-022-34059-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681748/
https://www.ncbi.nlm.nih.gov/pubmed/36414616
http://dx.doi.org/10.1038/s41467-022-34059-1

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