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Alveolar cell fate selection and lifelong maintenance of AT2 cells by FGF signaling
The lung’s gas exchange surface is comprised of alveolar AT1 and AT2 cells that are corrupted in several common and deadly diseases. They arise from a bipotent progenitor whose differentiation is thought to be dictated by differential mechanical forces. Here we show the critical determinant is FGF s...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681748/ https://www.ncbi.nlm.nih.gov/pubmed/36414616 http://dx.doi.org/10.1038/s41467-022-34059-1 |