Lactate causes downregulation of Helicobacter pylori adhesin genes sabA and labA while dampening the production of proinflammatory cytokines

Chronic inflammation induced by Helicobacter pylori is strongly associated with gastric cancer development, which is influenced by both bacterial virulence and host genetics. The sialic acid-binding adhesin SabA and the MUC5AC-binding adhesin LabA are important H. pylori virulence factors that facil...

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Detalles Bibliográficos
Autores principales: Somiah, Tanvi, Gebremariam, Hanna G., Zuo, Fanglei, Smirnova, Ksenija, Jonsson, Ann-Beth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681763/
https://www.ncbi.nlm.nih.gov/pubmed/36414643
http://dx.doi.org/10.1038/s41598-022-24311-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681763/
https://www.ncbi.nlm.nih.gov/pubmed/36414643
http://dx.doi.org/10.1038/s41598-022-24311-5

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